Before Tampa the Blues had Petro, Parayko, Edmonson, and Bortuzzo in the lineup. And last years Habs had Weber, Petry, Chariot, and Edmonson. This template has been pretty successful recently.
Avs have bucked the trend a bit, but they have had their playoff struggles and acquiring Manson at the deadline shows they were thinking about their lack of size. Makar and Toews at the top is also a supercharged Reilly and Brodie, so that helps as well mitigate the risk.
Unless Muzzin falls off a cliff next year I don't think there is a place for Sandin come next playoffs.