While I don't disagree that Buffalo absolutely could use some upgrades on the defense, I'm going to point out that this team leaking goals is not entirely because of 3rd pairing Dmen and bad goaltending. Adding a 2nd pairing Dman and a goalie will not solve the teams issues which are far bigger than just 1 or 2 players.
Structure, inexperience etc are a glaring problem from my point of view and until they ALL start playing a 200 foot game those things will not change.
Take a look at the teams with the highest expected goals against in the league. If you notice, the Sabres are the 5th worst and would likely be 4th worst if the games played was equal. Something else to point out here is that 4 of the 6 teams are all terrible. Buffalo and the Blues places in the standings do not reflect how bad they've been defensively. Both have been outscoring their problems more often than not, but that isn't something they can rely on.
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On the opposite side of that spectrum we have the the teams with the fewest expected goals against. There is a trend here as well. 5 of the top 6 are among the best teams in the league with Detroit being the anomaly. Detroit is easily explained by their poor offensive output.
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I know a lot of people on here cringe at advanced metrics, but these tend to line up with the standings most of the time. The eye test also tells us Buffalo gives up a ton of high danger chances, odd man rushes and overall high percentage scoring chances almost every game.
Any talk of if we had Ullmark, if we had Ekholm, if we had Chychrun doesn't fix a bigger issue. Sure adding them would definitely help, but can Don please institute some more defensive responsibility? They don't need to go full Barry Trotz here, but consistently playing defensively would help. Jersey plays a high tempo system and yet their players are still defensively responsible, I don't see why the Sabres can't as well.