If you're looking at forward line matchups, there's only one game you can go by this year, and it was with the Bruins dictating the matchups in Boston (February 3). Matthews didn't play any of the other ones, and I think the center spines were almost completely intact for both teams in the Feb 3rd game (except for Plekanec).
Bergeron (Heinen, Pastrnak) heavily matched against Matthews (Hyman, Nylander)
Krejci (DeBrusk, Spooner) played mostly against Bozak (JVR, Brown) and a decent amount against Moore and Kapanen
Riley Nash (Schaller, Backes) heavily matched against Kadri (Marleau, Marner)
Kuraly (Vatrano, Czarnik) played mostly against Kapanen and Komarov, no real matching though
From the Bruins angle, it looks like they only really care about putting Bergeron on Matthews and Riley Nash on the Kadri line. I think Nash has been the main reason (among forwards) for a successful season by the Bruins outside of the Bergeron line. Easily the 2nd best defensive forward on the team, filled in well when Bergeron went down, and has chipped in offensively as well. Contract year so he has an extra incentive as well.
No idea what the Leafs will do in Toronto as no Matthews in those games along with no Plekanec completely changes everything. For as long as I can remember though, Leafs have loved to put Kadri out against Bergeron.