The people who refuse to get the vaccine really infuriate me. However, I try to remember it's not a monolithic group. The people that have dug their heels in due to overtly political reasons, reasons to do with political influence--who would be getting a shot if someone they agreed with politically was advocating for it? f*** those people with a big, nasty tree branch.
I then remind myself there are other variables with the vaccine resistance as well. Anecdotally, People of Color have been skeptical of vaccinations (for obvious and f***ing horrifying historical reasons, among others), and I see it firsthand. I sent out a mandatory email to my organization requiring that everyone disclose their vaccination status; of the 420 or so that have currently responded, a hair under 400 are vaccinated or fully vaccinated. Of the 20-ish that aren't almost all indicated that they would not be getting a vaccine. Of this group, all but two were PoC--and the two that weren't, both said they wanted a vaccine but had serious health issues preventing it.
So, that's one thing I try to keep in mind--there are a large number of people who refuse to get a vaccine for idiotic reasons, but then there's also a significant amount of people who are refusing based on completely different objections/concerns (which, we can say are not legitimate, but we also have to acknowledge those fears are ingrained in certain cultures for legitimate reasons).
EDIT: To clarify, I understand there are people refusing the vaccine who a) aren't political crazies and b) aren't PoC who grew up leery of vaccines and medical professionals in general. There are plenty of other reason people refuse, many of which are valid, and many of which are f***ing dumb.