I've said it before, I wouldn't trade Panarin because I like scoring goals
I'd like to keep him too, but at 33 he's hitting the point where he can't be your #1 winger without an elite C. On top of that, how quickly is this turning around? Panarin is going to want to be on a contender, and not just a playoff team, but a legit cup contender.
You're not going to get better value than right now. If you wait for after this deadline, teams won't get two runs at it with him.
The only way you don't trade him is they plan on re-signing him. He'd have to take a discount from what he is currently making to have that work, and with those wingers you mentioned, and a few others on the way, you're better off making a move sooner than later.
You need young LHD and C options if you want to remake this roster for the future. Panarin can bring back pieces to do that.