History of hockey trades by general manager Jason Botterill - NHL Trade Tracker
'17 3rd to MTL for Beaulieu

'17 6th to VGK for expansion draft considerations

Ennis, Foligno, & '18 3rd to MIN for Scandella, Pominville, & '18 4th

Deslauriers to MTL for Redmond

'19 5th to DET for Wilson

EKane to SJS for Cond '19 1st, O'Regan, '20 4th

Fasching to ARZ for Hickey & Sislo

'19 Cond 4th to PIT for Sheary & Hunwick

ROR to STL for Sobotka, Berglund, Thompson, '19 1st, & '21 2nd

Pu, '19 2nd, '20 3rd, & '20 6th to CAR for Skinner

Baptiste to NASH for Dougherty

Fedun to DAL for '20 7th

Bailey to PHI for Leier

Guhle & '19 1st to ANA for Montour

Beaulieu to WIN for '19 6th

'21 2nd & '22 5th to VGS for Miller

'21 3rd to NYR for Vesey

Nylander to CHI for Jokiharju

Stephens to TBL for Spencer

Scandella to MTL for '20 4th

MTL '20 4th to CAL for Frolik
For those keeping score at home, there are two out of 21 trades that have made the Sabres better, IMO.
Adding Skinner and Jokiharju isn't enough given what Botterill has let leave over his time here.
And then you can look at his FA signings and it doesn't get better:
Signings - CapFriendly - NHL Salary Caps