The certainties, as I can see them:
Saad-Johansen-???
???-Dubinsky-???
Hartnell-Wennberg-???
???-Campbell-???
That leaves Foligno, Jenner, Atkinson, Calvert, Bourque, Clarkson, Boll and any prospects/AHLers to fill those remaining six spots.
Atkinson, Jenner and Foligno in some combination will fill the rest of the top two lines. I like the chemistry between Foligno and Dubi, so I'd probably slide Foligno on 2nd line RW, and I think Cam thrives with Johansen making plays for him, and Saad can only help that. That leaves Jenner on Dubi's left wing, which creates a real tough line with more than enough goalscoring punch.
That leaves the third and fourth lines. Optimally, I'd like to see Bjorkstrand or Milano step up in training camp and win that third-line RW spot, but fresh out of juniors I'm not ready to slot them in there. That leaves one major issue: of the bottom six wingers, only Calvert is particularly speedy. I'd like to get him on that Hartnell/Wennberg line, but that creates a Bourque/Campbell/Clarkson lumbering monstrosity on the fourth. Maybe Josh Anderson can earn one of those spots, but again, I'm not going to assume anything.
So these are my forward lines:
Saad-Johansen-Atkinson
Jenner-Dubinsky-Foligno
Hartnell-Wennberg-Clarkson
Calvert-Campbell-Bourque
Swap Clarkson and Bourque if you like; I've got them this way because I think Clarkson has a little more potential, but Bourque was more productive in his limited time in Columbus, so I could definitely see him being the incumbent third liner.
Defense is kind of a mess, but I'd like to see something like:
Johnson/Savard
Murray/Goloubef
Tyutin/Connauton
Boll and Prout are in the press box for now, maybe drawing in against teams where size/punching will be a factor.
As injuries happen, I think Rychel, Karlsson, and Anderson are the first callups for forwards, and Paliotta and Falk for defensemen.
I'm probably missing someone obvious, but I'm at work, so this is kind of off-the-cuff.