Sanderson is a year older than Werenski was, is used to playing 24-26 mins a night in college with heavy PK min, and there are other examples too, Provorov played 22 mins a night with 2:49 on the PK as a 20 yr old rookie, Heiskanen played 23 mins a night as a 19 yr old with 1:23 on the PK, Seider played 24 mins a night at 20 with 1:53 on the PK, no need to bubble wrap Sanderson.
I think it's reasonable to get him more time at 5v5, I've not yet seen a game where it's looked like he was overwhelmed by the mins he got, it would be different if he was struggling but the kid has arguably been our best defenceman.