Can't imagine so, no. He played in one of the highest scoring eras in hockey, and was one of the most talented players ever, while also having a physical advantage over most everyone else on the ice.
Suppose there were an NHL lockout in 15/16 and McDavid for some reason decides to play another season with the Otters instead of going to play literally anywhere else. He would have had to increase his P/G by 1.5 points per game compared to the previous season to eclipse Lemieux, while also playing 70 games. And he's probably the best player offensively since Lemieux.