I'm not sure how you can call some people's careers disappointing because of injuries. Guys like Bure, Neely and even Orr were great players that just didn't have the time to shine. I wouln't say they had disappointing careers, just unfinished.
The OP mentioned Bure and I have no idea how anyone could call him a disappointment. With Vancouver he was everything they expected and when he moved to the weaker Florida/NYR teams he produced amazing numbers playing with much less talent. Sadly, like Orr and others, a great career was cut short for Bure because of knee injuries. If you look at his totals from his last few season, where he barely played any games, his points per game were still stellar considering his knees and the fact he couldn't get a consistent rate of games in.
So, to me I can't really call a guy who performed amazingly while he played a disappointment because of injuries. Now, a guy like Lindros who never lived up to the hype, or Diagle who has only now started to fill some of his hype, I will whole-heartedly label as a disappointing career.