Ease of access and parking goes to Ponda Center easy.
Parking in downtown LA for Staples is a mess on weekdays, and very expensive.
Driving from Upland to DowntownLA/Stapler would be 90min without traffic regardless of which freeway you take ... so if you're looking at it from a budget/time perspective, Honda Center would be better bang for buck.
But you should still try go to the Stapler for some games on a weekend when traffic and parking are easier.
From a "things to do" before and after the game perspective, Downtown LA has really been revitalized in ~ last 5 years and the whole Staples/Microsoft Center/Fig and 7th area is 100x time more interesting than Honda Center's surrounding area. Unless you consider strip clubs and Hooters "high culture", there's not a lot to see in Honda Center's neighbourhood other than the Downtown disney shopping area.
Viewing angles is personal opinion. Nose bleeds in Staples look weird for me, you have to look basically straight down to see the ice. Ponda nose bleeds have better sight lines IMO, and people are in general friendlier to visiting fans. Ponda has more of a family vibe.
Ice level seats at Stapler are very good, but from a $ perspective, slightly more expensive than Ponda Center.