Though it looks the same on TV as it did in the old building (Bruins start the game defending the goal to the left with their bench opposite side left of center), it's actually flipped from the way it was prior to the venue change in 1995 (because TV cameras and booths are aiming south in the new building whereas they used to aim north). So in TD Garden, the Bruins aim west for the odd periods and east for the even periods (balcony section 320s are in the east end and 300s in the west end).
Like the Garden, Zamboni runway is in the NE corner of the rink (so on TV it's in the near left corner rather than the far right corner). Since TDG was built 9 inches north of Boston Garden, Causeway Street is still on the south side of the rink, Rte 93 on the east end of the rink and North Station rails aim north.
The "North End" of Boston is actually a short walk in a southeast direction from North Station, and the area immediately west of TDG include Mass Gen. Hosp. is considered the "West End." Hope that confuses everyone.