There are several college towns I'd like to go to and spend a Saturday in the fall. They range from places like Athens, GA (Probably the coolest town in the SEC outside of Nashville, the music scene I'd love to experience) to Lubbock, TX (would love to see a West Texas Sunset while taking in a Red Raiders night game). Some of these towns include Morgantown, Oxford, Baton Rouge, Norman, Lansing, Madison, State College, and South Bend. Been to Ann Arbor a couple of times and that is a great town.
The Florida Keys
New Orleans (Been before but this was 2 years after Katrina on a mission trip and we didn't really get to 'experience' the city)
Nashville and Memphis, mostly Nashville but I'd like to see Graceland and Beale Street
The lakes of Minnesota
Somewhere on Long Islands coast
San Diego
San Francisco
Seattle
Vail or Aspen, Colorado
Grand Canyon